Warm congratulations to SICGEN Antibodies, a brand represented by XMJ, on being selected as the 2024 "Best Antibody Development and Production Supplier" by Corporate America Today.

What is “Corporate America Today”？

Corporate America Today is an organization focused on the business sector, dedicated to recognizing success and innovation in the business field. With over 12 years of industry experience, it honors enterprises that have achieved outstanding performance in their respective industries on a global scale — spanning six continents and 163 countries. This organization is more than just an award-giving body; it is also a community consisting of over 427,554 subscribers, all of whom are committed to showcasing remarkable achievements in the business world.

SICGEN Antibodies

SICGEN Antibodies is a developer, manufacturer, and distributor of polyclonal antibodies for cell biology research. Founded in 2008, the company was spun off from the University of Coimbra by Portuguese scientist José Ramalho, who also serves as a researcher at NOVA University Lisbon.

SICGEN Antibodies focuses on the development, production, and marketing of innovative antibodies, which have achieved success across various fields of life science research. Notably, its antibodies targeting fluorescent proteins such as GFP, mCherry, and tdTomato have been featured in prestigious research journals including Nature, Cell, and Science. As of 2023, SICGEN has a product portfolio covering over 300 projects, primarily used in research techniques such as Western Blotting (WB), Immunofluorescence (IF), and Immunocytochemistry (IHC).

Antibodies Against GFP and mCherry Fluorescent Proteins

Green Fluorescent Protein (GFP) and the red fluorescent protein mCherry are two crucial fluorescent labeling tools in biological research. GFP was originally isolated from a jellyfish species called Aequorea victoria, while mCherry—also known as Cherry Fluorescent Protein or DsRed—is a monomeric red fluorescent protein isolated from corals of the genus Discosoma.

Owing to their unique spectral properties and stability, these two fluorescent proteins are widely used in molecular labeling and the localization of cellular components. The discovery and application of GFP and mCherry have significantly advanced the development of modern biological research. In 2008, Osamu Shimomura, Martin Chalfie, and Roger Y. Tsien were jointly awarded the Nobel Prize in Chemistry for their contributions to GFP research. These fluorescent proteins not only provide powerful tools for scientific research but also offer new perspectives for our understanding of life processes.

Application Cases

Immunostaining Results with GFP Antibody after Transfection of AtT-20 Cells for GFP-Rab27a Expression

Immunofluorescence Results of MCR Cells After Transfection for mCherry-Rab11a Expression, Fixation with Methanol, and Staining with anti-Rab11a Antibody (1:250 Dilution) and anti-mCherry Antibody

tdTomato, a Variant of mCherry

tdTomato is a dimer formed by the tandem expression of two mCherry monomers. This design aims to reduce protein aggregation, enhance fluorescence intensity, and minimize toxicity to cells or experimental animals. Therefore, tdTomato is more commonly used in in vivo experiments, as it provides a more stable and intense red fluorescent label.

Application Cases

Immunofluorescence Results of HEK293 Cells: Fixed with 4% PFA After cDNA Transfection and Stained with anti-tdTomato Antibody (1:50 Dilution)

Beijing XMJ is the authorized distributor of the SCIGEN brand in China, providing customers with comprehensive technical support and after-sales service. Follow the official WeChat public account of "XMJ Science and Technology" to discover more high-quality "star products" in the field of immunology!

Beijing XMJ Scientific Co., Ltd. has gathered global suppliers of high-quality antibodies, antibody-related products and services, including SCIGEN, Lifespan, MyBioSource, SeraCare (KPL), Agrisera, Absolute, Accurate, Nordic-MUbio, Exalpha, Everest and more. With well-known brands, high-quality products and a complete range of categories, it provides one-stop services for researchers in universities and scientific research institutions, as well as biopharmaceutical production enterprises.

If you are interested in the above products, please feel free to send email to info@xmjsci.com or visit XMJ's official website www.rmb365.cn for inquiries and orders.